Articles with "activation nicotinamide" as a keyword



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Activation of nicotinamide adenine dinucleotide phosphate oxidase is the primary trigger of epileptic seizures in rodent models

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Published in 2019 at "Annals of Neurology"

DOI: 10.1002/ana.25474

Abstract: Despite decades of epilepsy research, 30% of focal epilepsies remain resistant to antiseizure drugs, with effective drug development impeded by lack of understanding on how seizures are initiated. Here, we report the mechanism of seizure… read more here.

Keywords: adenine dinucleotide; nicotinamide adenine; dinucleotide phosphate; phosphate oxidase ... See more keywords