The activation of the Notch signaling pathway by UBE2C promotes the proliferation and metastasis of hepatocellular carcinoma
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DOI: 10.1038/s41598-024-72714-3
Abstract: UBE2C, a ubiquitin-conjugating enzyme, functions as an oncogene in different types of human cancers. Nonetheless, the exact influence of UBE2C on the development of HCC via regulation of ubiquitination remains uncertain. Here, we found that… read more here.
Keywords: hcc; activation; activation notch; metastasis ... See more keywords
Abstract PR06: Bacteroides fragilis: A potential pathogen orchestrating EMT and stemness in breast epithelial cells via concomitant activation of Notch and βcatenin axes
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DOI: 10.1158/1538-7445.mvc2020-pr06
Abstract: Background: The last decade established significant contributions of microbiome to many organ-specific cancers. A few recent studies suggested the existence of distinct breast microbiota and a shift in microbial community composition in diseased breast compared… read more here.
Keywords: breast; notch catenin; concomitant activation; activation notch ... See more keywords