ERK Activation Pathways Downstream of GPCRs.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2018.02.003
Abstract: GPCRs, the 7-TM receptors, represent a class of cell surface receptors which modulate a variety of physiological responses. The serpentine structure in addition to contributing the diversity of stimuli these receptors can sense also provides… read more here.
Keywords: erk activation; activation pathways; downstream gpcrs; activation ... See more keywords
Alternative platelet activation pathways and their role in neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2021.105512
Abstract: PURPOSE OF THE REVIEW The study of platelets in the context of neurodegenerative diseases is intensifying, and increasing evidence suggests that platelets may play an important role in the pathogenesis of neurodegenerative disorders. Therefore, we… read more here.
Keywords: neurodegenerative diseases; platelet activation; activation pathways; role ... See more keywords
Steric control of dioxygen activation pathways for MnII complexes supported by pentadentate, amide-containing ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Dalton transactions"
DOI: 10.1039/c9dt02682g
Abstract: Dioxygen activation at manganese centers is well known in nature, but synthetic manganese systems capable of utilizing O2 as an oxidant are relatively uncommon. These present investigations probe the dioxygen activation pathways of two mononuclear… read more here.
Keywords: mnii complexes; dioxygen activation; activation pathways; mnii ... See more keywords
Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1179355
Abstract: Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive surgery that has revolutionized the treatment of patients with devastating injuries, including those with limb losses or facial disfigurement. The transplanted units are typically comprised… read more here.
Keywords: vascularized composite; activation pathways; composite allotransplantation; rejection ... See more keywords
Targeting Platelet Activation Pathways to Limit Tumour Progression: Current State of Affairs
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15121532
Abstract: The association between cancer and a hypercoagulatory environment is well described. Thrombotic complications serve not only as a major mortality risk but the underlying molecular structure and function play significant roles in enhancing tumour progression,… read more here.
Keywords: platelet activation; tumour progression; progression; activation pathways ... See more keywords