P300-Targeted Acetylome Reveals a Role for HMGB1 Translocation in Central Cardiac Sympathetic Activation Post Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s524375
Abstract: Background Microglia/macrophage-dominated neuroinflammation in the hypothalamic paraventricular nucleus (PVN) critically mediates sympathetic overactivation, with the underlying mechanism remained elusive. Given that protein acetylation serves as a pivotal epigenetic modifier of inflammatory responses to immune-microenvironmental changes,… read more here.
Keywords: activation post; sympathetic activation; p300; activation ... See more keywords