The Smad2/3/4 complex binds miR‐139 promoter to modulate TGFβ‐induced proliferation and activation of human Tenon's capsule fibroblasts through the Wnt pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28011
Abstract: The activation and proliferation of human Tenon's fibroblasts (HTFs) play a vital role in the fibrosis in the pathology of the scar formation after the glaucoma filtration surgery. Transforming growth factor β1 (TGFβ1)/Smads signaling has… read more here.
Keywords: mir 139; activation proliferation; tgf induced; proliferation ... See more keywords
MicroRNA-708 represses hepatic stellate cells activation and proliferation by targeting ZEB1 through Wnt/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.172927
Abstract: Liver fibrosis is caused by a sustained wound healing response to chronic liver injury, and the activation of insubstantial hepatic stellate cells (HSCs) is the key process involved. The progression of liver fibrosis may be… read more here.
Keywords: zeb1; liver fibrosis; mir 708; activation proliferation ... See more keywords
Nuclear m6A reader YTHDC1 promotes muscle stem cell activation/proliferation by regulating mRNA splicing and nuclear export
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.08.07.503064
Abstract: Skeletal muscle stem cells (also known as satellite cells, SCs) are essential for muscle regeneration and the regenerative activities of SCs are intrinsically governed by gene regulatory mechanisms but the post-transcriptional regulation in SCs remains… read more here.
Keywords: m6a reader; nuclear export; export; activation proliferation ... See more keywords
Estrogen receptor β selective agonist ameliorates liver cirrhosis in rats by inhibiting the activation and proliferation of hepatic stellate cells
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DOI: 10.1111/jgh.13976
Abstract: The aim of this study is to explore the roles of estrogen receptor (ER) subtypes and corresponding agonists/antagonists on the development of cirrhosis and activation and proliferation of hepatic stellate cells (HSCs). read more here.
Keywords: proliferation hepatic; activation proliferation; estrogen receptor; hepatic stellate ... See more keywords
Activation and Proliferation of PD-1+ Kidney Double-Negative T Cells Is Dependent on Nonclassical MHC Proteins and IL-2.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2018080815
Abstract: BACKGROUND CD4- CD8- double-negative (DN) αβ T cells with innate-like properties represent a significant component of T cells in human and mouse kidneys. They spontaneously proliferate in the steady state and protect against ischemic AKI.… read more here.
Keywords: negative cells; double negative; activation proliferation; kidney ... See more keywords