Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40857-3
Abstract: Gallbladder carcinoma (GBC) is a biliary tract cancer with few treatment options and poor prognosis. Radical surgery is the only potentially curative treatment option but most patients diagnosed with GBC are unresectable. Thus, there is… read more here.
Keywords: mir 145; gallbladder; activation stat1; gallbladder carcinoma ... See more keywords
Loss of NFKB1 Results in Expression of Tumor Necrosis Factor and Activation of STAT1 to Promote Gastric Tumorigenesis in Mice.
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DOI: 10.1053/j.gastro.2020.06.039
Abstract: BACKGROUND & AIMS Activity of NFkB transcription factors and signaling via STAT are frequently altered in gastric cancer cells. Mice lacking NFKB1 (Nfkb1-/- mice) develop invasive gastric cancer and their gastric tissues have increased levels… read more here.
Keywords: nfkb1 mice; tnf; activation stat1; stat1 ... See more keywords
Activation of the STAT1 Pathway Accelerates Periodontitis in Nos3-/- Mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Dental Research"
DOI: 10.1177/0022034519858063
Abstract: Early studies on the etiology and pathogenesis of hypertension have shown that it has a considerable association with inflammation and the immune response as well as periodontitis. Clinical studies have also shown that hypertension can… read more here.
Keywords: stat1 pathway; nos3 mice; activation stat1; hypertension ... See more keywords