SUR1 as a New Therapeutic Target for Pulmonary Arterial Hypertension.
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DOI: 10.1165/rcmb.2021-0180oc
Abstract: Mutations in ABCC8 have been identified in pulmonary arterial hypertension (PAH). ABCC8 encodes SUR1, a regulatory subunit of the ATP-sensitive-potassium channel Kir6.2. However, the pathophysiological role of the SUR1/Kir6.2 channel in PAH is unknown. We… read more here.
Keywords: activation sur1; hypertension; pulmonary arterial; sur1 kir6 ... See more keywords