Macrophage activation syndrome due to Nocardia spp in a pediatric patient with cystic fibrosis
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DOI: 10.1002/ppul.24262
Abstract: Nocardia spp is a gram‐positive aerobic filamentous bacteria that causes pulmonary and systemic infections, especially in patients with immunosuppression or chronic lung diseases. It is rarely reported in children with cystic fibrosis. Macrophage activation syndrome… read more here.
Keywords: cystic fibrosis; activation syndrome; macrophage activation;
A Personalized Diagnostic and Treatment Approach for Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in Adults
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0439-x
Abstract: ObjectiveWe assessed the clinical features and outcomes based on therapeutic options adopted during hospital stay for adult patients with macrophage activation syndrome and secondary hemophagocytic lymphohistiocytosis (MAS/sHLH).MethodsWe conducted a retrospective chart review of all adult… read more here.
Keywords: adult; macrophage activation; treatment; mas shlh ... See more keywords
Macrophagic activation syndrome revealing disseminated multifocal tuberculosis: A case report of a rare clinical situation
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2022.103487
Abstract: Introduction Macrophage activation syndrome (MAS) is a rare but serious entity, sometimes triggered by an infectious agent, in particular by certain viruses or mycobacteria. Forms of tuberculosis complicated by MAS frequently occur in immunocompromised subjects.… read more here.
Keywords: tuberculosis; activation syndrome; report; case ... See more keywords
Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2016.09.016
Abstract: Macrophage activation syndrome (MAS) is a rare, life-threatening disease in which early diagnosis and aggressive therapeutic strategy may improve the outcome. Due to its rarity, epidemiologic data are still lacking. Hyperferritinemia is frequently associated with… read more here.
Keywords: adult; macrophage activation; diagnosis; time diagnosis ... See more keywords
Clinical spectrum and therapeutic management of systemic lupus erythematosus-associated macrophage activation syndrome: A study of 103 episodes in 89 adult patients.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.05.010
Abstract: OBJECTIVES Macrophage activation syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur during systemic lupus erythematosus (SLE). Data on MAS in adult SLE patients are very limited. The aim of this study is to… read more here.
Keywords: macrophage activation; study; 103 episodes; activation syndrome ... See more keywords
Macrophage activation syndrome in neonates born to mothers with adult-onset Still's disease: Perinatal effect of maternal IL-18.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical immunology"
DOI: 10.1016/j.clim.2019.07.005
Abstract: Overproduction of interleukin (IL)-18 is closely related to the pathogenesis of adult-onset Still's disease (AOSD) and the development of macrophage activation syndrome (MAS), a life-threating complication of AOSD. We reported three cases of MAS occurring… read more here.
Keywords: onset still; adult onset; macrophage activation; activation syndrome ... See more keywords
Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical immunology"
DOI: 10.1016/j.clim.2019.108252
Abstract: Our study aimed to compare the accuracy of serum biomarkers for the diagnosis of macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (s-JIA). Serum cytokine levels (neopterin, IL-18, and CXCL9 and soluble tumor necrosis… read more here.
Keywords: diagnosis macrophage; serum biomarkers; macrophage activation; biomarkers diagnosis ... See more keywords
Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome
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DOI: 10.1016/j.ijid.2020.09.016
Abstract: Objectives One-fifth of Covid-19 patients suffer a severely symptomatic, hyperinflammatory course, but specific causes remain unclear. Mast cells (MCs) are activated by SARS-CoV-2. Though only recently recognized, MC activation syndrome (MCAS), usually due to acquired… read more here.
Keywords: mcas; post covid; covid illness; covid ... See more keywords
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications
Sign Up to like & getrecommendations! Published in 2020 at "Life Sciences"
DOI: 10.1016/j.lfs.2020.117905
Abstract: In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international scientific community has joined forces to develop effective treatment strategies. The Angiotensin-Converting Enzyme (ACE) 2, is an essential receptor for cell… read more here.
Keywords: ace2 downregulation; macrophage activation; downregulation sars; activation syndrome ... See more keywords
Tofacitinib-induced remission in refractory adult-onset Still’s disease complicated by macrophage activation syndrome
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DOI: 10.1080/03009742.2020.1729405
Abstract: Adult-onset Still’s disease (AOSD) is rarely complicated by macrophage activation syndrome (MAS), which is also called secondary haemophagocytic lymphohistiocytosis (HLH) (1, 2). MAS is a life-thre... read more here.
Keywords: onset still; adult onset; macrophage activation; complicated macrophage ... See more keywords
Macrophage activation syndrome in a patient with systemic lupus erythematosus (SLE) and dual viremia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Community Hospital Internal Medicine Perspectives"
DOI: 10.1080/20009666.2020.1787811
Abstract: ABSTRACT Macrophage Activation Syndrome (MAS) is a potentially fatal inflammatory condition that can rapidly lead to multi-organ failure if inadequately treated. Also, known as secondary Hemophagocytic Lymphohistiocytosis (sHLH), MAS is commonly seen as a complication… read more here.
Keywords: macrophage activation; systemic lupus; erythematosus sle; lupus erythematosus ... See more keywords