MST1/2 Balance Immune Activation and Tolerance by Orchestrating Adhesion, Transcription, and Organelle Dynamics in Lymphocytes
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DOI: 10.3389/fimmu.2020.00733
Abstract: The STE20-like serine/threonine kinases MST1 and MST2 (MST1/2) are mammalian homologs of Hippo in flies. MST1/2 regulate organ size by suppressing the transcription factor YAP, which promotes proliferation. MST1 is predominantly expressed in immune cells,… read more here.
Keywords: immune activation; mst1; activation tolerance; balance immune ... See more keywords
Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.674048
Abstract: Dendritic cells (DCs) are paramount in initiating and guiding immunity towards a state of activation or tolerance. This bidirectional capacity of DCs sets them at the center stage for treatment of cancer and autoimmune or… read more here.
Keywords: immunity; activation tolerance; therapeutic liposomal; activation ... See more keywords