Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.
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DOI: 10.1016/j.metabol.2020.154182
Abstract: The impairment of podocyte protein filtration function caused by excessive mitochondrial calcium intake is a critical feature of diabetic nephropathy (DN). Ca2+ channel transient receptor potential cation channel subfamily V member 1 (TRPV1) has been… read more here.
Keywords: trpv1; endoplasmic reticulum; reticulum mitochondria; activation trpv1 ... See more keywords