Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming
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DOI: 10.1126/sciadv.aaw0025
Abstract: A transient activation of the unfolded protein response of the ER is a key factor of cellular reprogramming success. Somatic cells can be reprogrammed into pluripotent stem cells using the Yamanaka transcription factors. Reprogramming requires… read more here.
Keywords: essential step; step acquisition; activation uprer; activation ... See more keywords