Fatal Puumala Hantavirus Disease: Involvement of Complement Activation and Vascular Leakage in the Pathobiology
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DOI: 10.1093/ofid/ofx229
Abstract: Abstract The case-fatality rate of hantavirus disease depends strongly on the causative hantavirus, ranging from 0.1% to 40%. However, the pathogenesis is not fully understood, and at present no licensed therapies exist. We describe fatal… read more here.
Keywords: activation vascular; hantavirus disease; hantavirus; involvement complement ... See more keywords
Mineralocorticoid Receptor Activation in Vascular Insulin Resistance and Dysfunction
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DOI: 10.3390/ijms23168954
Abstract: Systemic insulin resistance is characterized by reduced insulin metabolic signaling and glucose intolerance. Mineralocorticoid receptors (MRs), the principal receptors for the hormone aldosterone, play an important role in regulating renal sodium handling and blood pressure.… read more here.
Keywords: activation vascular; insulin resistance; vascular insulin; insulin ... See more keywords