Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans
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DOI: 10.1155/cdr/1129181
Abstract: Background: Thymidine phosphorylase (TYMP) promotes platelet activation and thrombosis while suppressing vascular smooth muscle cell (VSMC) proliferation. Both processes are central to the development and progression of abdominal aortic aneurysms (AAAs). We hypothesize that TYMP… read more here.
Keywords: thymidine phosphorylase; activation vsmcs; activation; abdominal aortic ... See more keywords