Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.113919
Abstract: Achilles tendinopathy has a high re-injury rate and poor prognosis. Development of effective therapy for Achilles tendinopathy is important. Excessive accumulation of ROS and resulting oxidative stress are believed to cause tendinopathy. Overproduction of hydrogen… read more here.
Keywords: achilles tendinopathy; cellular mouse; activator aldh2; h2o2 ... See more keywords