Development of a Transcriptional Activator‐Like Effector Protein to Accurately Discriminate Single Nucleotide Difference
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200486
Abstract: Transcriptional activator‐like effector (TALE), a DNA‐binding protein, is widely used in genome editing. However, the recognition of the target sequence by the TALE is adversely affected by the number of mismatches. Therefore, the association constant… read more here.
Keywords: activator like; nucleotide difference; transcriptional activator; nucleotide ... See more keywords
Design and Application of DNA Modification-Specific Transcription-Activator-Like Effectors.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0876-0_29
Abstract: Transcription-activator like effectors (TALEs) are DNA-binding proteins used for genome targeting. TALEs contain a central domain of concatenated repeats, of which each selectively recognizes one nucleobase at the DNA major groove. Based on this simple… read more here.
Keywords: like effectors; activator like; transcription activator; dna ... See more keywords
Imaging-Based In Situ Analysis of 5-Methylcytosine at Low Repetitive Single Gene Loci with Transcription-Activator-Like Effector Probes
Sign Up to like & getrecommendations! Published in 2023 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00857
Abstract: Transcription-activator-like effectors (TALEs) are programmable DNA binding proteins that can be used for sequence-specific, imaging-based analysis of cellular 5-methylcytosine. However, this has so far been limited to highly repetitive satellite DNA. To expand this approach… read more here.
Keywords: transcription activator; gene loci; analysis; activator like ... See more keywords
Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor
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DOI: 10.1093/nar/gkac454
Abstract: Abstract DNA transcription is regulated by a range of diverse mechanisms and primarily by transcription factors that recruit the RNA polymerase complex to the promoter region on the DNA. Protein binding to DNA at nearby… read more here.
Keywords: transcription activator; dna; transcription; transcriptional regulation ... See more keywords
Insights into the diversity of transcription activator-like effectors (TALEs) in Indian pathotype strains of Xanthomonas oryzae pv. oryzae.
Sign Up to like & getrecommendations! Published in 2022 at "Phytopathology"
DOI: 10.1094/phyto-08-22-0304-sc
Abstract: Xanthomonas oryzae pv. oryzae (Xoo) is a major rice pathogen, and its genome harbours extensive inter-strain and inter-lineage variations. The emergence of highly virulent pathotypes of Xoo that can overcome major resistance genes deployed in… read more here.
Keywords: transcription activator; xanthomonas oryzae; oryzae oryzae; rice ... See more keywords
The Dynamic Transcription Activator -Like Effector Family of Xanthomonas.
Sign Up to like & getrecommendations! Published in 2022 at "Phytopathology"
DOI: 10.1094/phyto-10-22-0365-kd
Abstract: Transcription Activator-Like effectors (TALEs) are bacterial proteins that are injected into eukaryotic nucleus to act as transcriptional factors and function as key virulence factors of the phytopathogen Xanthomonas. TALEs induce the expression of host susceptibility… read more here.
Keywords: transcription activator; activator like; biology; effector ... See more keywords