Targeting Transcriptional Co-Activator PGC-1a for the Treatment of Sickle Cell Disease
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DOI: 10.1182/blood-2019-123959
Abstract: Sickle cell disease (SCD) is the most common inherited human hematologic disease, which causes hemolytic anemia, pain, disability, progressive multi-organ damage and early mortality. Clinical studies have shown that increased synthesis of fetal hemoglobin (HbF)… read more here.
Keywords: globin; activator pgc; disease; pgc ... See more keywords