Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group
Sign Up to like & getrecommendations! Published in 2020 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-020-00301-w
Abstract: In light of the accumulating evidence on the negative predictive value of soluble urokinase plasminogen activator receptor (suPAR), a group of experts from the fields of intensive care medicine, emergency medicine, internal medicine and infectious… read more here.
Keywords: urokinase plasminogen; medicine; activator receptor; emergency ... See more keywords
Urokinase Plasminogen Activator Receptor-PET with 68Ga-NOTA-AE105: First Clinical Experience with a Novel PET Ligand.
Sign Up to like & getrecommendations! Published in 2017 at "PET clinics"
DOI: 10.1016/j.cpet.2017.02.003
Abstract: Urokinase plasminogen activator receptor (uPAR) is a key component in proteolysis and extracellular matrix degradation during cancer invasion and metastasis. uPAR overexpression is an important biomarker for aggressiveness in several solid tumors and provides independent… read more here.
Keywords: urokinase plasminogen; pet; nota ae105; 68ga nota ... See more keywords
Soluble urokinase plasminogen activator receptor in type 1 diabetic children, relation to vascular complications.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of diabetes and its complications"
DOI: 10.1016/j.jdiacomp.2019.06.001
Abstract: BACKGROUND Endothelial dysfunction caused by chronic inflammation is the cornerstone of vascular complications in type 1 Diabetes-Mellitus (T1DM). Soluble Urokinase Plasminogen Activator Receptor (SuPAR) is a novel marker of inflammation and endothelial dysfunction. AIM To… read more here.
Keywords: vascular complications; urokinase plasminogen; plasminogen activator; activator receptor ... See more keywords
Elevated preoperative suPAR is a strong and independent risk marker for postoperative complications in patients undergoing major noncardiac surgery (SPARSE).
Sign Up to like & getrecommendations! Published in 2021 at "Surgery"
DOI: 10.1016/j.surg.2021.10.012
Abstract: BACKGROUND Patients undergoing major surgery are often at risk of developing postoperative complications. We investigated whether a preoperative marker of chronic inflammation, soluble urokinase plasminogen activator receptor, can aid in identifying patients at high risk… read more here.
Keywords: urokinase plasminogen; plasminogen activator; soluble urokinase; activator receptor ... See more keywords
Urokinase Plasminogen Activator Receptor-Mediated Targeting of a Stable Nanocomplex Coupled with Specific Peptides for Imaging of Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02697
Abstract: Targeting peptides are a promising tool for early diagnosis and therapy of cancer. Overexpression of urokinase plasminogen activator receptor (uPAR) leads to the progression of tumors including prostate, colorectal, ovarian, and breast cancers. To improve… read more here.
Keywords: urokinase plasminogen; microscopy; activator receptor; spectroscopy ... See more keywords
Soluble urokinase plasminogen activator receptor and functionally relevant coronary artery disease: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2038269
Abstract: Abstract Background Soluble urokinase plasminogen activator receptor (suPAR) is an emerging biomarker associated with anatomical CAD burden and cardiovascular outcomes including myocardial infarction (MI) and death. We aimed to validate previous findings of the prognostic… read more here.
Keywords: urokinase plasminogen; activator receptor; plasminogen activator; death ... See more keywords
The use of soluble urokinase plasminogen activator receptor (suPAR) as a marker of sepsis in the emergency department setting. A current review
Sign Up to like & getrecommendations! Published in 2019 at "Acta Clinica Belgica"
DOI: 10.1080/17843286.2019.1653519
Abstract: ABSTRACT Aim: The purpose of this review is to summarize all relevant publications regarding the use and validity of the soluble urokinase plasminogen activator receptor (suPAR) when used by clinicians in the emergency department (ED)… read more here.
Keywords: urokinase plasminogen; sepsis; activator receptor; supar ... See more keywords
P6436Soluble urokinase plasminogen activator receptor and functionally relevant coronary artery disease: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.1030
Abstract: The urokinase system is pivotal in the pathogenesis of atherosclerosis. Therefore, soluble urokinase plasminogen activator receptor (suPAR) concentrations may help in the detection of functionally relevant coronary artery disease (fCAD). To evaluate suPAR as diagnostic… read more here.
Keywords: urokinase plasminogen; fcad; death; supar concentrations ... See more keywords
Prognostic value of soluble urokinase‐type plasminogen activator receptor in coronary artery disease: A meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13867
Abstract: A potential inflammatory biomarker, soluble urokinase‐type plasminogen activator receptor (suPAR) has been utilized to assist the prognostic assessment of coronary artery disease (CAD) patients; however, outcomes have been inconsistent. The prognostic relevance of suPAR as… read more here.
Keywords: soluble urokinase; activator receptor; plasminogen activator; type plasminogen ... See more keywords
Soluble urokinase plasminogen activator receptor and survival in elective cardiac surgery
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.13953
Abstract: The study investigated the prognostic value of soluble urokinase plasminogen activator receptor (suPAR) in patients undergoing cardiac surgery and calculated a simplified biomarker score comprising suPAR, N‐terminal pro B‐type natriuretic peptide (NT‐proBNP) and age. read more here.
Keywords: soluble urokinase; plasminogen activator; cardiac surgery; urokinase plasminogen ... See more keywords
Soluble Urokinase Plasminogen Activator Receptor (suPAR) in Autoimmune Rheumatic and Non Rheumatic Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13040688
Abstract: The soluble urokinase plasminogen activator receptor (suPAR) is the bioactive form of uPAR, a membrane-bound glycoprotein, and it is primarily expressed on the surface of immunologically active cells. Mirroring local inflammation and immune activation, suPAR… read more here.
Keywords: soluble urokinase; plasminogen activator; supar; urokinase plasminogen ... See more keywords