Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
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DOI: 10.1021/acs.jmedchem.0c02154
Abstract: Herein we describe the discovery, mode of action, and preclinical characterization of the soluble guanylate cyclase (sGC) activator runcaciguat. The sGC enzyme, via the formation of cyclic guanosine monophoshphate, is a key regulator of body… read more here.
Keywords: soluble guanylate; guanylate cyclase; sgc; activator runcaciguat ... See more keywords