Identification of indole-based activators of insulin degrading enzyme.
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DOI: 10.1016/j.ejmech.2021.113982
Abstract: Insulin degrading enzyme (IDE) is a zinc metalloprotease that cleaves numerous substrates among which amyloid-β and insulin. It has been linked through genetic studies to the risk of type-2 diabetes (T2D) or Alzheimer's disease (AD).… read more here.
Keywords: identification indole; degrading enzyme; insulin degrading; activators insulin ... See more keywords