Small-molecule activators specific to adenine base editors through blocking the canonical TGF-β pathway
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DOI: 10.1093/nar/gkac742
Abstract: Abstract Adenine base editors (ABEs) catalyze A-to-G conversions, offering therapeutic options to treat the major class of human pathogenic single nucleotide polymorphisms (SNPs). However, robust and precise editing at diverse genome loci remains challenging. Here,… read more here.
Keywords: small molecule; activators specific; molecule activators; base editors ... See more keywords