Membrane-Active Antibacterial Agents Based on Calix[4]arene Derivatives: Synthesis and Biological Evaluation
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DOI: 10.3389/fchem.2022.816741
Abstract: Bacteria have developed increasing resistance to currently used antimicrobial agents. New classes of antimicrobial drugs are urgently required to fight drug-resistant pathogens. Here, we designed and synthesized a series of calix[4]arene derivatives as antibacterial agents… read more here.
Keywords: agents based; active antibacterial; membrane active; calix arene ... See more keywords
New Membrane Active Antibacterial and Antiviral Amphiphiles Derived from Heterocyclic Backbone of Pyridinium-4-Aldoxime
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DOI: 10.3390/ph15070775
Abstract: Quaternary ammonium salts (QAS) are irreplaceable membrane-active antimicrobial agents that have been widely used for nearly a century. Cetylpyridinium chloride (CPC) is one of the most potent QAS. However, recent data from the literature indicate… read more here.
Keywords: new membrane; active antibacterial; cpc; membrane active ... See more keywords