Supramolecular nanomotors with "pH taxis" for active drug delivery in the tumor microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr04415f
Abstract: Self-propelled nanomotors demonstrating autonomous motion in biologically relevant fuel are currently being studied to overcome the use of external physical or chemical stimuli as precise delivery agents. In this context, the tumor microenvironment (TME) with… read more here.
Keywords: drug delivery; delivery; active drug; tumor microenvironment ... See more keywords
A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonist
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2116368
Abstract: Abstract RO7119929 is being developed as an orally administered prodrug of the TLR7-specific agonist and active drug, RO7117418, for the treatment of patients with solid tumours. In this publication, we present a case study wherein… read more here.
Keywords: pharmacological active; active dose; prodrug; active drug ... See more keywords
Crystal structure analysis of the biologically active drug molecule riluzole and riluzolium chloride
Sign Up to like & getrecommendations! Published in 2019 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989019009022
Abstract: An investigation into the crystallization, crystal structure and packing analysis of the biologically active drug molecule riluzole and its derivative, the riluzolium chloride salt, has been carried out. read more here.
Keywords: drug molecule; active drug; biologically active; molecule riluzole ... See more keywords
More intensive hepatitis C virus care models promote adherence among people who inject drugs with active drug use: The PREVAIL study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13756
Abstract: Adequate adherence to medications for hepatitis C infection (HCV) among people who inject drugs (PWID) is crucial for cure. However, active drug use may interfere with optimal adherence. Using data from the PREVAIL study that… read more here.
Keywords: adherence; drug use; drug; care models ... See more keywords
Bioinspired Platform Conjugated Active Drug Delivery.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug targets"
DOI: 10.2174/1389450117666160602202850
Abstract: BACKGROUND The rapid emergence of nanotechnology and biotechnology has enabled revolutionary developments for drug delivery systems. Recently, drug delivery has attracted extensive research interest; applied to improve the functions of these carriers and their applications.… read more here.
Keywords: drug delivery; active drug; bioinspired platform; drug ... See more keywords