Long‐range molecular dynamics show that inactive forms of Protein Kinase A are more dynamic than active forms
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3556
Abstract: Many protein kinases are characterized by at least two structural forms corresponding to the highest level of activity (active) and low or no activity, (inactive). Further, protein dynamics is an important consideration in understanding the… read more here.
Keywords: active forms; molecular dynamics; range molecular; inactive forms ... See more keywords
Micro-RNAs in Response to Active Forms of Vitamin D3 in Human Leukemia and Lymphoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095019
Abstract: Non-coding micro-RNA (miRNAs) regulate the protein expression responsible for cell growth and proliferation. miRNAs also play a role in a cancer cells’ response to drug treatment. Knowing that leukemia and lymphoma cells show different responses… read more here.
Keywords: active forms; vitamin human; leukemia lymphoma; lymphoma cells ... See more keywords
Highly selective and sensitive measurement of active forms of FGF21 using novel immunocapture enrichment with LC-MS/MS.
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DOI: 10.4155/bio-2017-0208
Abstract: AIM Recombinant FGF21 analogs are under wide ranging investigations as a potential therapeutic agent for Type 2 diabetes, as well as other metabolic disorders. The endogenous FGF21 is often used as a surrogate pharmacodynamic(PD) biomarker… read more here.
Keywords: immunocapture; highly selective; active forms; selective sensitive ... See more keywords