The loud minority: Transcriptionally active HIV-1-infected cells survive, proliferate, and persist
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DOI: 10.1016/j.cell.2021.12.038
Abstract: The shock-and-kill strategy reactivates HIV-1 latent reservoir for immune clearance. Einkauf et al. found that some HIV-1-infected cells that persist and proliferate have transcriptionally active HIV-1 in permissive chromatin. Silent proviruses in repressive chromatin resist reactivation.… read more here.
Keywords: hiv infected; transcriptionally active; hiv; cells survive ... See more keywords