Engineering an active immunotherapy for personalized cancer treatment and prevention of recurrence.
Sign Up to like & getrecommendations! Published in 2023 at "Science advances"
DOI: 10.1126/sciadv.ade0625
Abstract: Breast cancer has been shown to be resistant to immunotherapies. To overcome this challenge, we developed an active immunotherapy for personalized treatment based on a smart nanovesicle. This is achieved by anchoring membrane-bound bioactive interleukin… read more here.
Keywords: treatment prevention; active immunotherapy; immunotherapy personalized; treatment ... See more keywords
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202216556
Abstract: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease and no preventive or curative therapy is available. CADASIL is caused by mutations in… read more here.
Keywords: active immunotherapy; brain capillaries; notch3 deposition; cadasil ... See more keywords
"Security dilemma": active immunotherapy before versus after radiation therapy alone or chemo-radiotherapy for newly diagnosed glioblastoma.
Sign Up to like & getrecommendations! Published in 2022 at "Folia medica"
DOI: 10.3897/folmed.64.e62981
Abstract: Management of glioblastoma should be aggressive and personalised to increase the quality of life. Many new therapies, such as active immunotherapy, increase the overall survival, yet they result in complications which render the search for… read more here.
Keywords: versus radiation; security dilemma; glioblastoma; dilemma active ... See more keywords