Articles with "active loop" as a keyword



Photo by clemono from unsplash

Theory of chromatin organization maintained by active loop extrusion.

Sign Up to like & get
recommendations!
Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2222078120

Abstract: The active loop extrusion hypothesis proposes that chromatin threads through the cohesin protein complex into progressively larger loops until reaching specific boundary elements. We build upon this hypothesis and develop an analytical theory for active… read more here.

Keywords: loop extrusion; chromatin organization; active loop;