Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00074
Abstract: The design of small molecules that inhibit disease-relevant proteins represents a longstanding challenge of medicinal chemistry. Here, we describe an approach for encoding this challenge-the inhibition of a human drug target-into a microbial host and… read more here.
Keywords: active natural; natural products; discovery; biologically active ... See more keywords
D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14071453
Abstract: Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also been traditionally used for medicinal purposes. Carob contains many nutrients and active natural products, and D-Pinitol is… read more here.
Keywords: carob; insulin regulation; pinitol active; active natural ... See more keywords