Mechanism of Action of pH-Triggered Membrane Active Peptides
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2839
Abstract: The plasma membrane insulates a cell from its outside environment, serving as a selectively impermeable barrier across which only small or hydrophobic molecules can pass. Although the membrane is necessary for life, it is also… read more here.
Keywords: membrane active; triggered membrane; action triggered; active peptides ... See more keywords
Application of the All-Hydrocarbon Stapling Technique in the Design of Membrane-Active Peptides.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01744
Abstract: The threats of drug resistance and new emerging pathogens have led to an urgent need to develop alternative treatment therapies. Recently, considerable research efforts have focused on membrane-active peptides (MAPs), a category of peptides in… read more here.
Keywords: active peptides; hydrocarbon stapling; membrane active; design ... See more keywords
Enzymatically Triggered Peptide–Lipid Conjugation of Designed Membrane Active Peptides for Controlled Liposomal Release
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c01387
Abstract: Possibilities for controlling the release of pharmaceuticals from liposomal drug delivery systems can enhance their efficacy and reduce their side effects. Membrane-active peptides (MAPs) can be tailored to promote liposomal release when conjugated to lipid… read more here.
Keywords: release; membrane active; conjugation; active peptides ... See more keywords
The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Technique Applied to the Study of Membrane-Active Peptides
Sign Up to like & getrecommendations! Published in 2018 at "Australian Journal of Chemistry"
DOI: 10.1071/ch18129
Abstract: (QCM-D) Technique Applied to the Study ofMembrane-Active Peptides Torsten John, Bernd Abel, and Lisandra L. Martin School of Chemistry, Monash University, Clayton, Vic. 3800, Australia. Leibniz Institute of Surface Engineering (IOM), and Wilhelm-Ostwald-Institute for Physical… read more here.
Keywords: chemistry; active peptides; applied study; qcm technique ... See more keywords
A unified model of transient poration induced by antimicrobial peptides
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2510294122
Abstract: Significance Membrane active peptides are cationic amphipathic molecules that disrupt biological membranes to perform their function. Antimicrobial peptides, which are permeabilizing, kill bacteria and cancer cells, making them promising candidates to fight drug-resistance; cell-penetrating peptides… read more here.
Keywords: model transient; unified model; membrane active; transient poration ... See more keywords
Current progress in kokumi-active peptides, evaluation and preparation methods: a review.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2020.1837726
Abstract: Kokumi is a complex sensation characterized by thickness, mouthfulness and continuity. Kokumi-active peptides, which are distributed in many kinds of food, induce a rich and long-lasting mouthfeel of food. Aimed to provide a comprehensive overview… read more here.
Keywords: kokumi active; kokumi; evaluation; active peptides ... See more keywords
Endolysins and membrane-active peptides: innovative engineering strategies against gram-negative bacteria
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2025.1603380
Abstract: Endolysins, bacteriophage-encoded peptidoglycan hydrolases, offer promising potential in antibacterial therapy, including treatments targeting gram-negative bacteria. While these enzymes naturally act primarily on gram-positive bacteria, their application against gram-negative pathogens is more challenging due to the… read more here.
Keywords: gram negative; membrane active; negative bacteria; endolysins membrane ... See more keywords
Characterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1324418
Abstract: Background and aims: The increasing incidence of cardiovascular diseases has created an urgent need for safe and effective anti-thrombotic agents. Leech, as a traditional Chinese medicine, has the effect of promoting blood circulation and removing… read more here.
Keywords: anti thrombotic; thrombosis; tail; app aph ... See more keywords
Antimicrobial and Cell-Penetrating Peptides: Understanding Penetration for the Design of Novel Conjugate Antibiotics
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11111636
Abstract: Antimicrobial peptides (AMPs) are short oligopeptides that can penetrate the bacterial inner and outer membranes. Together with cell-penetrating peptides (CPPs), they are called membrane active peptides; peptides which can translocate across biological membranes. Over the… read more here.
Keywords: antibiotics antimicrobial; active peptides; cell penetrating; penetrating peptides ... See more keywords
Recent Progress in Microencapsulation of Active Peptides—Wall Material, Preparation, and Application: A Review
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12040896
Abstract: Being a natural active substance with a wide variety of sources, easy access, significant curative effect, and high safety, active peptides have gradually become one of the new research directions in food, medicine, agriculture, and… read more here.
Keywords: application; active peptides; technology; microencapsulation ... See more keywords
Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315437
Abstract: Peptides are potential therapeutic alternatives against global diseases, such as antimicrobial-resistant infections and cancer. Venoms are a rich source of bioactive peptides that have evolved over time to act on specific targets of the prey.… read more here.
Keywords: active peptides; peptides venoms; applications antibiotic; venoms applications ... See more keywords