Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.127655
Abstract: A recent study of AHSCT for active relapsing-remitting multiple sclerosis (RRMS) showed efficacy in preventing disease worsening. However, the immunologic basis for efficacy remains poorly defined. MS pathology is known to be driven by inflammatory… read more here.
Keywords: pre existing; active rrms; multiple sclerosis; transplantation ... See more keywords
Highly active RRMS and ocrelizumab after failure of alemtuzumab therapy
Sign Up to like & getrecommendations! Published in 2020 at "BMC Neurology"
DOI: 10.1186/s12883-020-01789-y
Abstract: Background A high multiple sclerosis activity while on alemtuzumab is rather uncommon compared to moderate-efficacy drugs. The purpose of this case report is to present a case of a 37-year-old female patient with bronchial asthma… read more here.
Keywords: active rrms; rrms ocrelizumab; highly active; alemtuzumab therapy ... See more keywords