Biological Activities Evaluation of Enantiopure Isoxazolidine Derivatives: In Vitro, In Vivo and In Silico Studies
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DOI: 10.1007/s12010-018-2868-2
Abstract: A series of enantiopure isoxazolidines (3a–c) were synthesized by 1,3-dipolar cycloaddition between a (−)-menthone-derived nitrone and various terminal alkenes. The screened compounds were evaluated for their antioxidant activity by two in vitro antioxidant assays, including… read more here.
Keywords: activities evaluation; biological activities; compared standard; evaluation enantiopure ... See more keywords
Synthesis and Antiproliferatory Activities Evaluation of Multi-Substituted Isatin Derivatives
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DOI: 10.3390/molecules26010176
Abstract: A series of multi-substituted isatin derivatives were synthesized using the powerful Sandmeyer reaction. The structures of these derivatives were confirmed by 1H-NMR, 13C-NMR, and HR-MS. Inhibition of proliferation activities of these derivatives against human leukemia… read more here.
Keywords: activities evaluation; antiproliferatory activities; substituted isatin; multi substituted ... See more keywords