Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular Signaling.
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DOI: 10.1016/j.tcb.2017.06.002
Abstract: Gliomas and leukemias remain highly refractory to treatment, thus highlighting the need for new and improved therapeutic strategies. Mutations in genes encoding enzymes involved in the tricarboxylic acid (TCA) cycle, such as the isocitrate dehydrogenases… read more here.
Keywords: activities idh1; oncogenic activities; idh1 mutations; mutations epigenetics ... See more keywords