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Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666180529081328
Abstract: 4-MP is a potent competitive inhibitor of ADH activity with an affinity about a 1000 times more than toxic alcohols. 4-MP was shown to reduce the formation of toxic metabolites in lethal methanol and ethylene…
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Keywords:
methyl pyrazole;
animals humans;
pyrazole animals;
activities methyl ... See more keywords
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Published in 2019 at "Molecules"
DOI: 10.3390/molecules24030451
Abstract: 4,4-Dimethylsterols and 4-methylsterols are sterol biosynthetic intermediates (C4-SBIs) acting as precursors of cholesterol, ergosterol, and phytosterols. Their accumulation caused by genetic lesions or biochemical inhibition causes severe cellular and developmental phenotypes in all organisms. Functional…
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Keywords:
metabolism biological;
activities methyl;
methyl sterols;
biological activities ... See more keywords