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Published in 2023 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300067
Abstract: The discovery of new therapeutic drugs is heavily reliant on the structural diversity and pharmacological properties of heterocyclic compounds. Pyridine heterocyclic-related medicines, in particular, have garnered considerable attention due to their wide pharmacological activities and…
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Keywords:
activities novel;
review biological;
cyanopyridine derivatives;
novel cyanopyridine ... See more keywords
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Published in 2020 at "Drug Development Research"
DOI: 10.1002/ddr.21745
Abstract: In this article, a series of 29 new pyrimidine N‐acylhydrazone hybrids were synthesized and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi protozoa that cause the neglected diseases cutaneous leishmaniasis and Chagas disease, respectively.…
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Keywords:
antiparasitic activities;
activities novel;
novel pyrimidine;
acylhydrazone hybrids ... See more keywords
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Published in 2020 at "Journal of Chemical Research"
DOI: 10.1177/1747519819901251
Abstract: Eight glycosyl benzoxazole derivatives are synthesized by nucleophilic addition reactions of glycosyl isothiocyanate with o-aminophenol in tetrahydrofuran. The reaction conditions are optimized, and good yields (86%–94%) were obtained. The structures of all new products are…
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Keywords:
anticholinesterase activities;
synthesis anticholinesterase;
novel glycosyl;
benzoxazole derivatives ... See more keywords
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Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19082318
Abstract: A series of sixteen ring-substituted N-arylcinnamamides was prepared and characterized. Primary in vitro screening of all the synthesized compounds was performed against Staphylococcus aureus, three methicillin-resistant S. aureus strains, Mycobacterium tuberculosis H37Ra, Fusarium avenaceum, and…
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Keywords:
spectrum biological;
biological activities;
phenylprop enamide;
activities novel ... See more keywords