Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning.
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DOI: 10.1016/j.cels.2018.09.002
Abstract: Alternative splicing (AS) is generally regulated by trans-splicing factors that specifically bind to cis-elements in pre-mRNAs. The human genome encodes ∼1,500 RNA binding proteins (RBPs) that potentially regulate AS, yet their functions remain largely unknown.… read more here.
Keywords: machine learning; modeling predicting; activities trans; splicing factors ... See more keywords