Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells
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DOI: 10.1080/14756366.2021.1933466
Abstract: Abstract In this paper, a set of 3-methylquniazolinone derivatives were designed, synthesised, and studied the preliminary structure-activity relationship for antiproliferative activities. All target compounds performed significantly inhibitory effects against wild type epidermal growth factor receptor… read more here.
Keywords: tumour cells; preliminary structure; activities tumour; activity relationship ... See more keywords