Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics
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DOI: 10.1371/journal.ppat.1007697
Abstract: Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment. This may help explaining a significant discrepancy between antibiotic efficacy in vitro and in vivo,… read more here.
Keywords: activity aminoglycoside; aminoglycoside antibiotics; host; proton motive ... See more keywords