Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-62339-7
Abstract: Proteases have been implicated in the development of many pathological conditions, including cancer. Detection of protease activity in diseased tissues could therefore be useful for diagnosis, prognosis, and the development of novel therapeutic approaches. Due… read more here.
Keywords: probody; protease; antibody; activity biological ... See more keywords
ProAct: quantifying the differential activity of biological processes in tissues, cells, and user-defined contexts.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad421
Abstract: The distinct functions and phenotypes of human tissues and cells derive from the activity of biological processes that varies in a context-dependent manner. Here, we present the Process Activity (ProAct) webserver that estimates the preferential… read more here.
Keywords: processes tissues; proact; biological processes; activity biological ... See more keywords