Two-photon excited fluorescence (TPEF) may be useful to identify macrophage subsets based on their metabolic activity and cellular responses in atherosclerotic plaques.
Sign Up to like & getrecommendations! Published in 2020 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2020.07.017
Abstract: BACKGROUND AND AIMS Atherosclerosis is characterized by the formation of lipid plaques within the arterial wall. In such plaques, the massive and continuous recruitment of circulating monocyte-derived macrophages induces inflammation, leading to plaque destabilization and… read more here.
Keywords: atherosclerotic plaques; cellular responses; metabolic activity; macrophage ... See more keywords
Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy models
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn9350
Abstract: De novo point mutations in GNAO1, gene encoding the major neuronal G protein Gαo, have recently emerged in patients with pediatric encephalopathy having motor, developmental, and epileptic dysfunctions. Half of clinical cases affect codons Gly203,… read more here.
Keywords: gnao1 encephalopathy; activity cellular; cellular interactions; gtpase activity ... See more keywords
Kynurenic Acid Modulates the Expression of Genes and the Activity of Cellular Antioxidant Enzymes in the Hypothalamus and Hippocampus in Sheep
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25179428
Abstract: Kynurenic acid (KYNA), a tryptophan metabolite, is believed to exert neuromodulatory and neuroprotective effects in the brain. This study aimed to examine KYNA’s capacity to modify gene expression and the activity of cellular antioxidant enzymes… read more here.
Keywords: cat; activity cellular; kynurenic acid; antioxidant enzymes ... See more keywords