Discovery of Novel 7-Hydroxy-5-oxo-4,5-dihydrothieno[3,2-b]pyridine-6-carboxamide Derivatives with Potent and Selective Antifungal Activity against Cryptococcus Species.
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DOI: 10.1021/acs.jmedchem.2c00794
Abstract: Cryptococcus neoformans and Cryptococcus gattii can cause fatal invasive infections, especially in immunocompromised patients. However, few antifungal drugs are available to help treat cryptococcosis. In this study, by compound library screening, we presented the first… read more here.
Keywords: antifungal activity; p163 0892; cryptococcus; activity cryptococcus ... See more keywords