Evaluation of cholinesterase inhibitory activity and cytotoxicity of synthetic derivatives of di- and triterpene metabolites from Pinus silvestris and Dipterocarpus alatus resins
Sign Up to like & getrecommendations! Published in 2020 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-020-02566-9
Abstract: A series of hydroxy-, oximino-, lactame, arylidene, N-methylpiperazinyl amide, isoxazole, pyrimidine derivatives of dipterocarpol, quinopimaric, and dammarenolic acids were synthesized and evaluated for cholinesterase inhibitory activity and cytotoxicity. All of the compounds were weak inhibitors… read more here.
Keywords: inhibitory activity; cholinesterase inhibitory; activity cytotoxicity;
Antibacterial activity and cytotoxicity of flavonoids compounds isolated from Pseudarthria hookeri Wight & Arn. (Fabaceae)
Sign Up to like & getrecommendations! Published in 2018 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2017.11.001
Abstract: Abstract Pseudarthria hookeri is used in Africa for the treatment of pneumonia, cough, abdominal pains and diarrhea. However the bioactive constituents underlying the health benefits associated with P. hookeri remain unknown. In this study, the… read more here.
Keywords: isolated pseudarthria; compounds isolated; antibacterial activity; pseudarthria hookeri ... See more keywords
Antimicrobial Activity and Cytotoxicity of Ag(I) and Au(I) Pillarplexes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00584
Abstract: The biological activity of four pillarplex compounds featuring different metals and anions was investigated. The toxicity of the compounds against four bacterial strains [Bacillus subtilis (ATCC6633), Staphylococcus aureus (ATCC6538), Escherichia coli (UVI isolate), Pseudomonas aeruginosa],… read more here.
Keywords: antimicrobial activity; activity; cytotoxicity pillarplexes; activity cytotoxicity ... See more keywords
Hemolytic Activity, Cytotoxicity, and Antimicrobial Effects of Silver Nanoparticles Conjugated with Lincomycin or Cefazolin
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213709
Abstract: The overuse of antibiotics has led to the emergence of resistant bacteria. A good alternative is silver nanoparticles, which have antibacterial activity against Gram-negative and Gram-positive bacteria, including multidrug-resistant strains. Their combination with already known… read more here.
Keywords: activity cytotoxicity; hemolytic activity; silver nanoparticles; activity ... See more keywords
Antioxidant Activity and Cytotoxicity of Aromatic Oligosulfides
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123961
Abstract: Natural or synthetic antioxidants with biomimetic fragments protect the functional and structural integrity of biological molecules at a minimum concentration, and may be used as potential chemotherapeutic agents. This paper is devoted to in silico… read more here.
Keywords: disulfide; activity cytotoxicity; antioxidant activity; activity ... See more keywords
Hemolytic Activity and Cytotoxicity of Synthetic Nanoclays with Montmorillonite Structure for Medical Applications
Sign Up to like & getrecommendations! Published in 2023 at "Nanomaterials"
DOI: 10.3390/nano13091470
Abstract: The factors influencing the appearance of toxicity in samples of synthetic montmorillonite with a systematically changing chemical composition Nax(Al, Mg)2-3Si4O10(OH)2 nH2O, which are potentially important for their use in medicine as drug carriers, targeted drug… read more here.
Keywords: activity cytotoxicity; synthetic nanoclays; cytotoxicity synthetic; hemolytic activity ... See more keywords