The longitudinal effect of biologic use on patient outcomes (disease activity, function, and disease severity) within a rheumatoid arthritis registry
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04649-4
Abstract: Biologics effectively manage symptoms and disease activity in rheumatoid arthritis (RA), but their long-term effects remain unclear. Longitudinal data were examined from the Brigham and Women’s Rheumatoid Arthritis Sequential Study (BRASS) registry. Linear regression modeled… read more here.
Keywords: disease activity; severity; rheumatoid arthritis; activity function ... See more keywords
The Impact of Physical Activity and Function on Falls in Assisted Living Residents.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of aging and physical activity"
DOI: 10.1123/japa.2018-0291
Abstract: The purpose of this study was to describe physical activity and function of older adults in assisted living communities and test the association between moderate and vigorous activity and falls. This study used baseline data… read more here.
Keywords: activity function; assisted living; physical activity; activity ... See more keywords
Structure, activity and function of the lysine methyltransferase SETD5
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1089527
Abstract: SET domain-containing 5 (SETD5) is an uncharacterized member of the protein lysine methyltransferase family and is best known for its transcription machinery by methylating histone H3 on lysine 36 (H3K36). These well-characterized functions of SETD5… read more here.
Keywords: structure activity; activity function; methyltransferase; lysine methyltransferase ... See more keywords
Structure, Activity and Function of the NSD3 Protein Lysine Methyltransferase
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11080726
Abstract: NSD3 is one of six H3K36-specific lysine methyltransferases in metazoans, and the methylation of H3K36 is associated with active transcription. NSD3 is a member of the nuclear receptor-binding SET domain (NSD) family of histone methyltransferases… read more here.
Keywords: function nsd3; nsd3; nsd3 protein; structure activity ... See more keywords
Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11111132
Abstract: Among the nine mammalian protein arginine methyltransferases (PRMTs), PRMT8 is unusual because it has restricted expression in the nervous system and is the only membrane-bound PRMT. Emerging studies have demonstrated that this enzyme plays multifaceted… read more here.
Keywords: protein arginine; function prmt8; activity function; protein ... See more keywords
Special Issue “Structure, Activity, and Function of Protein Methyltransferases”
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12030405
Abstract: Post-translational modifications (PTMs) largely expand the functional diversity of the proteome [...]. read more here.
Keywords: special issue; structure activity; function protein; protein methyltransferases ... See more keywords