In vitro antiproliferative activity of glabridin derivatives and their in silico target identification
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Research"
DOI: 10.1080/14786419.2018.1530228
Abstract: Abstract Novel Mannich base derivatives of glabridin were synthesized and their antiproliferative activity were performed along with our previously reported glabridin-chalcone hybrids molecules (GCHMs) against various human cell lines MDA-MB-231 (breast adenocarcinoma), HEK-293 (embryonic kidney… read more here.
Keywords: silico target; activity glabridin; glabridin derivatives; antiproliferative activity ... See more keywords
Dehydrozingerone enhances the fungicidal activity of glabridin against Saccharomyces cerevisiae and Candida albicans.
Sign Up to like & getrecommendations! Published in 2023 at "Letters in applied microbiology"
DOI: 10.1093/lambio/ovad040
Abstract: Drug resistance commonly occurs when treating immunocompromised patients with fungal infections. Dehydrozingerone-a phenolic compound isolated from the rhizome of Zingiber officinale-inhibits drug efflux in Saccharomyces cerevisiae by overexpression of the ATP-binding cassette (ABC) transporter Pdr5p.… read more here.
Keywords: glabridin; activity glabridin; dehydrozingerone enhances; activity ... See more keywords