Inhibition of pseudoperoxiadse activity of human red blood cell hemoglobin by methocarbamol.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2016.09.049
Abstract: After red blood cells lysis, hemoglobin is released to blood circulation. Hemoglobin is carried in blood by binding to haptoglobin. In normal individuals, no free hemoglobin is observed in the blood, because most of the… read more here.
Keywords: red blood; hemoglobin; inhibition; activity human ... See more keywords
3-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethylpropan-1-ammonium perchlorate: Synthesis, crystal structure, docking study and in vitro anticancer activity against the human hepatomas cell line (Hep G2)
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131006
Abstract: Abstract 2-(3-(Dimethylamino)propyl)isoindoline-1,3‑dione (DAPID) has been synthesized and utilized to produce 3-(1,3-dioxoisoindolin-2-yl)-N,N-dimethyl propan-1-ammonium perchlorate (DIDAP). Both DAPID and DIDAP were characterized using different spectroscopic techniques. Structure of the DIDAP has been determined using single crystal X-ray… read more here.
Keywords: ammonium perchlorate; activity human; didap; anticancer activity ... See more keywords
Lysyl oxidase activity in human skin is increased by chronic ultraviolet radiation exposure and smoking
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.14959
Abstract: Lifestyle choices, such as tobacco smoking and sunbathing can lead to premature skin ageing1. These extrinsic accelerators of the ageing process cause profound changes to the abundance and arrangement of the elastic fibres and fibrillar… read more here.
Keywords: increased chronic; human skin; oxidase activity; lysyl oxidase ... See more keywords
The activity of human enhancers is modulated by the splicing of their associated lncRNAs
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1009722
Abstract: Pervasive enhancer transcription is at the origin of more than half of all long noncoding RNAs in humans. Transcription of enhancer-associated long noncoding RNAs (elncRNA) contribute to their cognate enhancer activity and gene expression regulation… read more here.
Keywords: elncrna splicing; enhancer; activity; human enhancers ... See more keywords
FcγR Binding and ADCC Activity of Human IgG Allotypes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00740
Abstract: Antibody dependent cellular cytotoxicity (ADCC) is an Fc-dependent effector function of IgG important for anti-viral immunity and anti-tumor therapies. NK-cell mediated ADCC is mainly triggered by IgG-subclasses IgG1 and IgG3 through the IgG-Fc-receptor (FcγR) IIIa.… read more here.
Keywords: adcc activity; igg; igg allotypes; activity human ... See more keywords
The antitumor activity of human Vγ9Vδ2 T cells is impaired by TGF-β through significant phenotype, transcriptomic and metabolic changes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1066336
Abstract: Despite significant advances, the eradication of cancer remains a clinical challenge which justifies the urgent exploration of additional therapeutic strategies such as immunotherapies. Human peripheral Vγ9Vδ2 T cells represent an attractive candidate subset for designing… read more here.
Keywords: activity human; antitumor activity; human cells; metabolic changes ... See more keywords
Corrigendum: Antifungal Activity of the Human Uterine Cervical Stem Cells Conditioned Medium (hUCESC-CM) Against Candida albicans and Other Medically Relevant Species of Candida
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01297
Abstract: [This corrects the article DOI: 10.3389/fmicb.2018.02818.]. read more here.
Keywords: corrigendum antifungal; activity human; uterine cervical; human uterine ... See more keywords
Preservation of Anti-cytomegalovirus Activity in Human Milk Following High-Pressure Processing Compared to Holder Pasteurization
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.918814
Abstract: Pasteurized donor human milk is recommended for hospitalized preterm infants when mother’s own milk is unavailable. Our aim was to compare the antiviral activity of human milk processed by Holder pasteurization (HoP) or high-pressure processing… read more here.
Keywords: human milk; activity human; anti cytomegalovirus; activity ... See more keywords
Characterization of a Neutral Sphingomyelinase Activity in Human Serum and Plasma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032467
Abstract: Alterations of sphingolipids and their metabolizing enzymes play a role in various diseases. However, peripheral biomarkers for such changes are limited. Particularly, in the increasingly reported involvement of neutral sphingomyelinase (NSM) with four described isoforms… read more here.
Keywords: activity human; serum; nsm activity; neutral sphingomyelinase ... See more keywords
LL-37 Triggers Antimicrobial Activity in Human Platelets
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032816
Abstract: Platelets play a crucial role in hemostasis and the immune response, mainly by recognizing signals associated with vascular damage. However, it has recently been discovered that the antimicrobial peptide LL-37 activates platelets in functions related… read more here.
Keywords: triggers antimicrobial; antimicrobial activity; human platelets; activity human ... See more keywords
Measurement of Microcystin and Nodularin Activity in Human Urine by Immunocapture-Protein Phosphatase 2A Assay
Sign Up to like & getrecommendations! Published in 2019 at "Toxins"
DOI: 10.3390/toxins11120729
Abstract: Microcystins (MC) and nodularin (NOD) are toxins released by cyanobacteria during harmful algal blooms. They are potent inhibitors of protein phosphatases 1 and 2A (PP1 and PP2A) and cause a variety of adverse symptoms in… read more here.
Keywords: human urine; nodularin activity; activity human; microcystin nodularin ... See more keywords