Resurfacing promotes antibacterial activity of a lipid A–binding nanobody
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2509305122
Abstract: Significance Antibodies have been explored to treat antibiotic-resistant infections, but identifying leads with direct antibacterial action has proven challenging. Here, we screened a library of nanobodies for antimicrobial potential and identified a nanobody that binds… read more here.
Keywords: antibacterial activity; activity lipid; promotes antibacterial; lipid binding ... See more keywords
Apelin‐mediated deamidation of HMGA1 promotes tumorigenesis by enhancing SREBP1 activity and lipid synthesis
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DOI: 10.1111/cas.15515
Abstract: Enhanced fatty acid synthesis provides proliferation and survival advantages for tumor cells. Apelin is an adipokine, which serves as a ligand of G protein–coupled receptors that promote tumor growth in malignant cancers. Here, we confirmed… read more here.
Keywords: srebp1 activity; hmga1; apelin; synthesis ... See more keywords
Association of dietary pattern and physical activity with lipid-related indices among Chinese population: a cross-sectional study
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DOI: 10.1186/s12944-020-01420-6
Abstract: Background and objectives To explore the relationship between dietary patterns, physical activity and lipid-related indices in Chinese Population. Methods and study design This study included 21,472 (72.3% men) participants aged 16 to 78 years. Data of… read more here.
Keywords: related indices; lipid related; chinese population; activity lipid ... See more keywords