Reduction of the Double Bond of 6-Arylvinyl-1,2,4-trioxanes Leads to a Remarkable Increase in Their Antimalarial Activity against Multidrug-Resistant Plasmodium yoelii nigeriensis in a Swiss Mice Model
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c05041
Abstract: Novel 6-arylethyl-1,2,4-trioxanes6a–i and 7a–i are easily accessible in one step from the diimide reduction of 6-arylvinyl-1,2,4-trioxanes 5a–i. All of these new trioxanes were assessed for their oral antimalarial activity against multidrug-resistant Plasmodium yoelii nigeriensis in… read more here.
Keywords: protection; arylvinyl trioxanes; antimalarial activity; dose days ... See more keywords
Trends in ceftazidime‐avibactam activity against multidrug‐resistant organisms recovered from respiratory samples of cystic fibrosis patients
Sign Up to like & getrecommendations! Published in 2018 at "Transplant Infectious Disease"
DOI: 10.1111/tid.12955
Abstract: Cystic fibrosis (CF) patient are frequently colonized by multidrug resistant micro-organisms. About 5% and 10% of patients are colonized by Burkholderia cepacia complex (Bcc) and Stenotrophomonas maltophilia respectively, and up to 50% of Pseudomonas aeruginosa isolates… read more here.
Keywords: ceftazidime avibactam; multidrug; cystic fibrosis; multidrug resistant ... See more keywords