Enhanced bioavailability and antihypertensive activity of nisoldipine loaded nanoemulsion: optimization, cytotoxicity and uptake across Caco-2 cell line, pharmacokinetic and pharmacodynamic studies
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DOI: 10.1080/03639045.2020.1724128
Abstract: Abstract Objective: The present study explored the antihypertensive activity of nisoldipine in oil in water nanoemulsion to improve its oral bioavailability via intestinal lymphatic uptake. Methods: Nanoemulsion was prepared by ultrasonication technique using Peceol, Cremophor… read more here.
Keywords: bioavailability; drug; nanoemulsion; antihypertensive activity ... See more keywords