Cationic Amphiphilic Polymers with Antimicrobial Activity for Oral Care Applications: Eradication of S. mutans Biofilm.
Sign Up to like & getrecommendations! Published in 2017 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.6b01598
Abstract: The antibacterial and antibiofilm activities of cationic amphiphilic methacrylate polymers against cariogenic bacterium S. mutans were investigated. Cationic homopolymer PE0 and copolymer PE31 containing 31 mol % of ethyl methacrylate were synthesized by reversible addition-fragmentation… read more here.
Keywords: amphiphilic polymers; cationic amphiphilic; antimicrobial activity; polymers antimicrobial ... See more keywords
Cytotoxicity and Antimicrobial Activity of Oral Rinses In Vitro
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/4019723
Abstract: While oral rinses used for cosmetic purposes only do not necessarily have to be antiseptic, antimicrobial activity is required for medical indications, including oral and periodontal surgery. So the question arises—is the antimicrobial activity of… read more here.
Keywords: antimicrobial activity; rinses containing; cosmetic purposes; oral rinses ... See more keywords
RX 3117: Activity of an oral antimetabolite nucleoside in subjects with pancreatic cancer–Preliminary results of stage II of the phase Ia/IIb study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.4_suppl.396
Abstract: 396Background: RX-3117 is an oral small-molecule antimetabolite, cyclopentyl pyrimidyl nucleoside that is activated by uridine cytidine kinase 2. RX-3117 has shown efficacy in xenograft models of gemcitabine resistant pancreatic, bladder and colorectal cancer. Data from… read more here.
Keywords: stage phase; 3117 activity; study; pancreatic cancer ... See more keywords
Acetylation Enhances the Anticancer Activity and Oral Bioavailability of 5-Demethyltangeretin
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DOI: 10.3390/ijms232113284
Abstract: A kind of hydroxylated polymethoxyflavone (PMFs) existing in the citrus genus, 5-Demethyltangeretin (5-DTAN), has been reported to possess several bioactivities in vitro and in vivo. The aim of this study was to investigate whether acetylation… read more here.
Keywords: oral bioavailability; anticancer activity; acetylation; dtan ... See more keywords
Modified Polymeric Nanoparticles Exert In Vitro Antimicrobial Activity Against Oral Bacteria
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DOI: 10.3390/ma11061013
Abstract: Polymeric nanoparticles were modified to exert antimicrobial activity against oral bacteria. Nanoparticles were loaded with calcium, zinc and doxycycline. Ions and doxycycline release were measured by inductively coupled plasma optical emission spectrometer and high performance… read more here.
Keywords: polymeric nanoparticles; oral bacteria; nanoparticles reduction; antimicrobial activity ... See more keywords