LAUSR

HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia

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0 Published in 2017 at "Leukemia"

DOI: 10.1038/leu.2017.3

Abstract: HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia read more here.

Keywords: activity required; leukemogenesis acute; hdac3 activity; leukemia ... See more keywords

Corrigendum: Agrp neuron activity is required for alcohol-induced overeating

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0 Published in 2017 at "Nature Communications"

DOI: 10.1038/ncomms15668

Abstract: This corrects the article DOI: 10.1038/ncomms14014. read more here.

Keywords: required alcohol; corrigendum agrp; neuron activity; agrp neuron ... See more keywords

eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function

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1 Published in 2020 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaa336

Abstract: Abstract As cells encounter adverse environmental conditions, such as hypoxia, oxidative stress or nutrient deprivation, they trigger stress response pathways to protect themselves until transient stresses have passed. Inhibition of translation is a key component… read more here.

Keywords: required tirna; stress; translation; small rnas ... See more keywords

iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis

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1 Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.03056

Abstract: Objectives: Fibrosis is a hallmark of systemic sclerosis (SSc), an intractable disease where innovative strategies are still being sought. Among novel anti-fibrotic approaches, mesenchymal stromal/stem cell (MSC)-based therapy appears promising. Previously, we reported anti-fibrotic effects… read more here.

Keywords: anti fibrotic; ssc; systemic sclerosis; mice ... See more keywords

TPL2 kinase activity is required for Il1b transcription during LPS priming but dispensable for NLRP3 inflammasome activation

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0 Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1496613

Abstract: The NLRP3 inflammasome complex is an important mechanism for regulating the release of pro-inflammatory cytokines, IL-1β and IL-18, in response to harmful pathogens. Overproduction of pro-inflammatory cytokines has been linked to cryopyrin-associated periodic syndrome, arthritis,… read more here.

Keywords: inflammasome activation; tpl2 kinase; kinase activity; activity required ... See more keywords