Biological activity and safety profile of monoterpenes against Plutella xylostella L. (Lepidoptera: Plutellidae)
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-08751-y
Abstract: Plutella xylostella L. is a cosmopolitan pest of wild and cultivated crucifer vegetables worldwide. It has developed resistance to almost all commercial chemicals, making them one of the most problematic field pests in China. The… read more here.
Keywords: biological activity; safety profile; activity safety; plutella xylostella ... See more keywords
A double-blind placebo-controlled randomized phase II trial assessing the activity and safety of regorafenib in non-adipocytic patients previously treated with both chemotherapy and pazopanib.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cancer"
DOI: 10.1016/j.ejca.2019.12.001
Abstract: BACKGROUND Metastatic soft tissue sarcomas (STSs) management remains an unmet medical need. We assessed the activity and safety of regorafenib in patients with metastatic non-adipocytic STS who were previously treated with both chemotherapy and pazopanib.… read more here.
Keywords: non adipocytic; activity safety; versus; placebo ... See more keywords
Antibacterial activity, safety and preservative effect of aminoethyl-phloretin on the quality parameters of salmon fillets
Sign Up to like & getrecommendations! Published in 2020 at "Lwt - Food Science and Technology"
DOI: 10.1016/j.lwt.2019.108874
Abstract: Abstract Aminoethyl-phloretin (AEP), a novel water-soluble phloretin derivative, was synthesized from phloretin and 2-bromine ethylamine. Its antibacterial activity, safety, and preservative effect on salmon were studied. The structure of AEP was verified with UV, IR,… read more here.
Keywords: phloretin; aminoethyl phloretin; activity safety; antibacterial activity ... See more keywords
Antimicrobial activity and safety applications of meso-tetra(4-pyridyl)platinum(II) porphyrin.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.12.038
Abstract: Tetra-platinated(II) porphyrin hexafluorophosphate compound (4-PtTPyPor) was synthetized and along 5,10,15,20-tetrakis(4-pyridyl)porphyrin (4-TPyPor), evaluated about the antimicrobial activity and safety. The effect was evaluated with and without light exposition. The antimicrobial activity was analyzed by microdilution and… read more here.
Keywords: platinum porphyrin; antimicrobial activity; pyridyl; activity safety ... See more keywords
Activity and Safety Optimization of Mesoricin: A Dual-Domain Antifungal Peptide from Mesorhizobium sp.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c02917
Abstract: Cryptococcus neoformans infections pose a significant global health threat. This study introduces mesoricin, a novel dual-domain antimicrobial peptide (AMP) scaffold derived from Mesorhizobium sp. identified using an in silico quantitative antifungal activity index (AFI). The… read more here.
Keywords: dual domain; domain; mesorhizobium; activity safety ... See more keywords
Evaluation of the anticoagulant activity and safety of PMPC-PSSS and PMPC-PVBTAC block copolymers.
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DOI: 10.1039/d5bm00406c
Abstract: Unfractionated heparin (UFH) remains a widely used anticoagulant; however, its use is associated with several limitations, including an elevated risk of bleeding, the potential for heparin-induced thrombocytopenia, and the necessity for frequent monitoring. Alternative anticoagulants… read more here.
Keywords: pmpc; block copolymers; block; activity safety ... See more keywords
Activity and safety of crizotinib in patients with advanced, metastatic alveolar soft part sarcoma (ASPS) with rearrangement of TFE3: European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 CREATE.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11540
Abstract: 11540Background: ASPS is an orphan disease associated with rearrangement of transcription factor E3 (TFE3), leading to abnormal MET expression. We assessed crizotinib in pts with ASPS (NCT01524926)... read more here.
Keywords: advanced metastatic; metastatic alveolar; activity safety; safety crizotinib ... See more keywords
The clinical activity and safety of anlotinib combined with anti-PD-1 antibodies in patients with advanced solid tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15081
Abstract: e15081Background: Anlotinib (AL3818) is a novel multi-target tyrosine kinase inhibitor (TKI) for tumor angiogenesis and tumor cell proliferation. Modulation of vascular endothelial growth factor-me... read more here.
Keywords: clinical activity; activity safety; anlotinib combined; combined anti ... See more keywords
Activity and safety of cabozantinib (cabo) in brain metastases (BM) from metastatic renal cell carcinoma (mRCC): An international multicenter study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.310
Abstract: 310Background: Cabo shows robust clinical activity in mRCC. Patients (pts) with BM have been underrepresented in clinical trials and effective systemic therapy is lacking. We retrospectively charac... read more here.
Keywords: activity safety; cabozantinib cabo; activity; cabo brain ... See more keywords