Structure‐Activity Studies of Truncated Latrunculin Analogues with Antimalarial Activity
Sign Up to like & getrecommendations! Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000399
Abstract: Malarial parasites employ actin dynamics for motility, and any disruption to these dynamics renders the parasites unable to effectively establish infection. Therefore, actin presents a potential target for malarial drug discovery, and naturally occurring actin… read more here.
Keywords: truncated latrunculin; latrunculin analogues; studies truncated; activity studies ... See more keywords
Synthetic access to thiolane-based therapeutics and biological activity studies.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113659
Abstract: Secondary metabolites isolated from bioactive extracts of natural sources iteratively pioneer the research in drug discovery. Modern medicine is often inspired by bioactive natural products or the bio-functional motifs embedded in them. One of such… read more here.
Keywords: thiolane based; biological activity; activity studies; based therapeutics ... See more keywords
The Photodynamic Anticancer and Antibacterial Activity Properties of a Series of meso-Tetraarylchlorin Dyes and Their Sn(IV) Complexes
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DOI: 10.3390/molecules28104030
Abstract: A series of tetraarylchlorins with 3-methoxy-, 4-hydroxy- and 3-methoxy-4-hydroxyphenyl meso-aryl rings (1-3-Chl) and their Sn(IV) complexes (1-3-SnChl) were synthesized and characterized so that their potential utility as photosensitizer dyes for use in photodynamic therapy (PDT)… read more here.
Keywords: antibacterial activity; series; activity; activity studies ... See more keywords
Biocompatibility and Hemolytic Activity Studies of Synthesized Alginate-Based Polyurethanes
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DOI: 10.3390/polym14102091
Abstract: Many investigators have focused on the development of biocompatible polyurethanes by chemical reaction of functional groups contained in a spacer and introduced in the PU backbone or by a grafting method on graft polymerization of… read more here.
Keywords: hemolytic activity; alginate based; biocompatibility hemolytic; activity studies ... See more keywords